Clinical Study by BIOTRONIK Reveals Novel Technique to Detect Cardiovascular Disease

BIOTRONIK has announced that the results of a clinical research conducted by Home Monitoring in Cardiac Resynchronization Therapy (Home-CARE) have been published in the European Journal of Heart Failure.

The Home-CARE study was conducted on 515 patients and was conducted across many centres internationally. The study aimed at creating an automated algorithm that took multiple parameters related to cardiovascular disease that was provided by BIOTRONIK Home Monitoring System into consideration and dynamically foresee death and hospitalization for patients suffering from the disease. The main parameters that were considered for analysing the cardiovascular status of the heart failure patients were mean heart rate, heart rate variability and patient activity. By using of all these parameters together, 65.4% sensitivity was observed in identification of cardiovascular death and hospitalizations with a specificity of 99.5%.

Professor Stefan Sack explained that the study believed that by coming up with an algorithm which took into consideration several parameters, the overall risk ability could be improved with patients having implanted cardiac devices. This algorithm was the brain child of BIOTRONIK which was used for early detection of cardiovascular events based on the data from the Home Monitoring system. The Home Monitoring system from BIOTRONIK is capable of transmitting accurate, real-time data by remotely monitoring the diagnostic data. By using this data for research and development purposes it is possible to design advanced diagnostic algorithms that includes novel sensor technology and to accurately study their influence on clinical administration, patient outcomes and health economic burden. The Vice President of Global Marketing at BIOTRONIK, Marlou Janssen, believes that the new algorithm designed by them will prove useful in building HF predictor applications in future and enhance the patient management systems through BIOTRONIK Home Monitoring.